新しい研究により、伝書鳩は地球の磁場を感知するために、肝臓にある鉄分を豊富に含んだ免疫細胞を利用していることが明らかになった。この発見は、鳥類が悪天候時でも長距離を飛行できる仕組みについて、新たな説明をもたらすものである。
ボン大学やマックス・プランク動物行動学研究所などの研究チームは、肝臓内のマクロファージが鉄分を蓄積し、強い磁気特性を示すことを発見した。これらの細胞は神経線維の近くに位置しており、磁気信号が脳へ伝達される経路が存在することを示唆している。
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A team led by David Julius, the 2021 Nobel Prize winner in Medicine, has described the molecular mechanism by which intestinal tuft cells signal the brain to suppress appetite during parasitic infections. Published today in Nature, the study identifies communication via acetylcholine and serotonin that activates the vagus nerve. The finding could aid treatments for conditions like irritable bowel syndrome.
Researchers at UCLA have identified senescent immune cells, dubbed 'zombie' cells, that accumulate in aging livers and contribute to fatty liver disease. By eliminating these cells in mice, the team reversed liver damage and reduced body weight, even on an unhealthy diet. The findings, published in Nature Aging, suggest similar mechanisms may drive human liver conditions.
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Cancer cells that reduce MHC class I—a common way to evade CD8+ “killer” T cells—may become more vulnerable to destruction by CD4+ “helper” T cells through ferroptosis, according to research led by Baylor College of Medicine and collaborators at the University of Michigan and published in Nature Immunology.
Researchers at Harvard Medical School have uncovered a hidden map of smell receptors in mice noses, revealing neat stripes instead of random distribution. This structure aligns with brain mapping, challenging prior assumptions about olfaction. The findings, published April 28 in Cell, could aid treatments for smell loss.
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Researchers at Dongguk University in Seoul have developed a magnetically controlled switch for turning on genes inside cells, as detailed in a recent Cell paper. The technique uses a specific electromagnetic signal to activate genes in mice and human cells. Critics, however, question the plausibility of the results and point to potential flaws in the study.