3D-printed structures could speed up car t-cell therapy

Dansk

Researchers have developed 3D-printed gels that mimic lymph nodes to improve the production of CAR T-cells for cancer treatment. The approach increased success rates and sped up cell growth compared with standard methods. It may help lower costs and expand access to the therapy worldwide.

The standard process for making CAR T-cells involves extracting T-cells from a patient, genetically engineering them with a virus to target cancer, and multiplying them over several weeks. This can cost more than £280,000 per round and often takes up to a month, limiting availability especially in lower-income countries.

Relaterede artikler

3D cryo-expansion microscopy image of a killer T cell's immune synapse with a tumor cell, revealing nanoscale killing machinery organization.
Billede genereret af AI

Cryo-expansion microscopy captures 3D architecture of killer T cells at the immune synapse, including in human tumors

Rapporteret af AI Billede genereret af AI Faktatjekket

Researchers from the University of Geneva and Lausanne University Hospital report they have visualized, in three dimensions and under near-native conditions, how cytotoxic T cells organize their killing machinery at the immune synapse. The work, published in Cell Reports, applies cryo-expansion microscopy to human T cells and to tumor tissue samples, providing nanoscale views intended to support immunology and cancer research.

Stiffening cancer cells boosts car t-cell therapy in mice

Researchers have found that making cancer cells stiffer can enhance the effectiveness of car t-cell therapy against aggressive tumors. In experiments with mice, the approach led to complete tumor disappearance in some cases. The findings were presented recently at a conference in London.

CAR-T cell therapy shows early promise for HIV control

Rapporteret af AI

A small study has found that CAR-T cell therapy may offer a new way to manage HIV over the long term. The approach, already used to treat certain cancers, involves engineering a patient’s own immune cells.

Sundhed

Engineered phages redirect vaccine immunity to eradicate tumors in mice

Sundhed

Fully human antibody blocks tumor growth and metastasis in preclinical models of aggressive prostate cancer

Sundhed

FDA-approved drug shows promise against rare liver cancer

Silica nanoparticles eliminate prostate tumors in mice

Researchers at Weill Cornell Medicine have developed tiny silica nanoparticles that destroyed aggressive prostate cancer tumors in mice while boosting the immune system. The treatment led to complete remissions when combined with immunotherapy.

Caribou Biosciences presents car-t updates at healthcare conference

Rapporteret af AI

Caribou Biosciences discussed progress on its off-the-shelf CAR-T therapies during a presentation at the Bank of America Global Healthcare Conference on May 13. Chief executive Rachel Haurwitz highlighted Phase I data for two programs that target lymphoma and multiple myeloma.

mandag d. 13. juli 2026, 05.10

Cell therapy keeps four children alive years after brain cancer diagnosis

mandag d. 29. juni 2026, 21.11

USC scientists create renewable supply of cancer-fighting cells

tirsdag d. 2. juni 2026, 11.34

Protein found to limit CAR T-cell therapy effectiveness

fredag d. 29. maj 2026, 15.41

Virus injection halts pancreatic tumor growth in trial

mandag d. 25. maj 2026, 18.52

McGill researchers use reversible drug approach to boost natural killer cells against hard-to-treat cancers

Dette websted bruger cookies

Vi bruger cookies til analyse for at forbedre vores side. Læs vores privatlivspolitik for mere information.
Afvis