A 2023 study found that falling levels of the protein Menin in the hypothalamus drive multiple signs of aging in mice. Restoring the protein or supplementing with the amino acid D-serine improved memory and other measures.
Researchers at Xiamen University in China showed that Menin levels drop sharply in a specific part of the hypothalamus as mice age. When they lowered Menin in younger animals, the mice developed brain inflammation, weaker bones, thinner skin, poorer balance, memory loss, and shorter lifespans.
