Cowboys host Cardinals in key Monday Night Football matchup

The Dallas Cowboys will host the Arizona Cardinals on Monday Night Football in Week 9, with both teams aiming to improve their NFC playoff chances. Dallas enters as a 3.5-point favorite at AT&T Stadium, while Arizona will start backup quarterback Jacoby Brissett due to Kyler Murray's foot injury. The over-under total is set at 53.5 points.

The Arizona Cardinals (2-5) face the Dallas Cowboys (3-4-1) on Monday, November 3, 2025, at 8:15 p.m. ET from AT&T Stadium in Arlington, Texas. Both teams are looking to rebound after recent losses: Arizona fell 27-23 to the Green Bay Packers on October 19, while Dallas lost 44-24 at Denver on October 26. The Cardinals sit fourth in the NFC West and are 1-2 on the road this season. The Cowboys are second in the NFC East and unbeaten at home in regulation (2-0-1).

Dallas holds a commanding all-time series lead of 56-35-1, though Arizona has won seven of the last eight meetings. In the latest odds from DraftKings Sportsbook, the Cowboys are 3.5-point favorites with a money line of -179, while the Cardinals are +150 underdogs. The total points over-under is 53.5.

For Dallas, quarterback Dak Prescott has fueled an offense averaging 30.8 points per game, second in the NFL. Through eight games, Prescott has completed 204 of 290 passes for 2,069 yards, 16 touchdowns, and five interceptions, posting a 101.6 passer rating. He has also rushed for 87 yards and one touchdown on 25 carries. Wide receiver George Pickens leads the receiving corps with 43 catches for 685 yards and six touchdowns, including eight receptions for 134 yards and two scores in a September 28 tie with Green Bay.

Arizona will turn to Jacoby Brissett for his third straight start, as Kyler Murray (foot) is questionable and not expected to play. Brissett has gone 52 of 80 for 599 yards, four touchdowns, and one interception in his two prior starts, with a 97.7 rating. Tight end Trey McBride is the Cardinals' top target, hauling in 47 receptions for 421 yards and four touchdowns over seven games. He caught 10 passes for 74 yards and two scores in the loss to Green Bay.

Expert Tom Fornelli, on a 9-2 run in Cardinals picks, leans under the total but highlights a key X-factor for the spread. A separate preview predicts a 30-23 Cowboys win, citing Dallas's offensive advantages against Arizona's 25th-ranked pass defense.

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