Gut Microbiota

Animal study raises new questions about gut effects of SNAC, an ingredient used in oral semaglutide tablets

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Researchers at Adelaide University report that salcaprozate sodium (SNAC)—an absorption enhancer used in oral semaglutide tablets—was associated with changes in gut bacteria and inflammation markers in an animal study conducted over 21 days. The authors said the findings do not demonstrate harm in humans but argue that longer-term research is needed as oral options for obesity treatment expand.