Sex Differences
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Drug combo extends remaining lifespan of frail elderly male mice by about 70%
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A combination of oxytocin and an Alk5 inhibitor significantly extended remaining lifespan and improved health in very old, frail male mice, according to research from the University of California, Berkeley. The treatment increased their remaining life by about 73% but did not lengthen lifespan in females, underscoring key sex differences in aging biology and in responses to longevity therapies.