Lakers visit Spurs in Western Conference clash

The Los Angeles Lakers face the San Antonio Spurs in a pivotal Western Conference matchup on Wednesday night. Both teams enter the game with strong records, but injuries could play a significant role in the outcome. The Spurs are favored by 7.5 points in this rematch of a split season series.

The Los Angeles Lakers (23-11) head to San Antonio to take on the Spurs (25-11) at 9:30 p.m. ET from Frost Bank Center. The Lakers are riding a three-game winning streak, capped by a 111-103 victory over the New Orleans Pelicans on Tuesday. Meanwhile, the Spurs have dropped their last two games, including a narrow 106-105 loss to the Memphis Grizzlies on the same night.

Injuries loom large for both sides. For the Lakers, LeBron James is listed as questionable with sciatica and a foot issue, while Austin Reaves and Rui Hachimura are ruled out due to calf injuries. On the Spurs' side, Victor Wembanyama is questionable with a knee problem, and Devin Vassell is sidelined with an adductor injury.

The teams have split their two encounters this season, adding intrigue to this contest. Betting odds list the Spurs as 7.5-point favorites, with an over/under of 235.5 points. Advanced simulations suggest the under is likely, projecting a combined total of 232 points. This prediction aligns with recent trends: the under has hit in the Spurs' last three games and the Lakers' last two, as well as nine of San Antonio's last 11 overall. Both teams are playing on the second night of back-to-backs, a situation where the under has prevailed in four of five Spurs games this season. The Lakers have also failed to reach the total in their last five road contests, compounded by their shorthanded roster.

This matchup highlights the competitive balance in the Western Conference, where every game can shift standings. Fans can stream the action on Fubo.

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The Oklahoma City Thunder host the San Antonio Spurs on January 13, 2026, aiming to snap a 0-3 skid against their Western Conference rivals. With the Thunder leading the West at 33-7 and the Spurs close behind at 27-12, this matchup at Paycom Center carries high stakes. Injuries to key players like Devin Vassell and Isaiah Hartenstein add intrigue to the 8 p.m. ET tipoff.

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