Cell Therapy
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Duke-NUS unveils BrainSTEM atlas to guide Parkinson’s research
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Duke-NUS Medical School researchers, working with the University of Sydney, have developed BrainSTEM—a two-tier, single-cell atlas of the developing human brain that profiles nearly 680,000 cells. Published online in Science Advances on October 31, 2025, the resource focuses on midbrain dopaminergic neurons, flags off‑target cell types in lab-grown models, and will be released openly for the research community.
In a small cell therapy trial, 10 out of 12 participants with type 1 diabetes no longer required supplemental insulin one year after treatment. This represents a promising advancement in diabetes management.