Mike McClure reveals top NFL DFS picks for Week 18 Saturday

Daily Fantasy expert Mike McClure has shared his optimal lineups for the Week 18 Saturday NFL slate, featuring the Buccaneers versus Panthers and Seahawks versus 49ers. With playoff implications on the line, both games promise full effort from starters. McClure highlights key players like Jaxon Smith-Njigba and Mike Evans for high-value DFS rosters.

The Week 18 Saturday NFL schedule kicks off with the Carolina Panthers facing the Tampa Bay Buccaneers at 4:30 p.m. ET, where the Buccaneers are favored by 2.5 points with a total of 44. Later, the Seattle Seahawks host the San Francisco 49ers at 8 p.m. ET, with the 49ers as 1.5-point underdogs and an over/under of 49.5. These matchups carry significant weight for the playoff picture, ensuring no major resting of players.

DFS specialist Mike McClure, who has amassed over $2 million in career winnings, relies on a simulation model that factors in matchups, trends, and injuries to identify value. His 2023 successes include tying for first in the DraftKings Millionaire Maker twice and winning the FanDuel Million once. For this slate, McClure recommends rostering Seahawks wide receiver Jaxon Smith-Njigba, a third-year player leading the league with 1,709 receiving yards and ranking top 10 in major categories. Targeted 25 times over the past two weeks, he faces a 49ers defense that ranks 21st in fantasy points allowed to wide receivers.

McClure also targets Buccaneers wide receiver Mike Evans, who returned from a two-month collarbone injury on November 11. In his three games back, Evans has seen 28 targets and scored two touchdowns. He has a strong history against the Panthers, with eight touchdowns in their last six meetings. The player pool includes other notables like Christian McCaffrey, Rico Dowdle, and Bucky Irving, but McClure identifies an additional undervalued option for tournament potential.

For those building FanDuel or DraftKings lineups, McClure's stacks and advice aim to maximize returns on this high-stakes doubleheader.

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Dramatic night game action at Raymond James Stadium: Buccaneers vs. Panthers in pivotal NFC South title clash.
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Buccaneers face Panthers in pivotal NFC South showdown

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The Tampa Bay Buccaneers host the Carolina Panthers on Saturday in a winner-takes-all battle for the NFC South title and a playoff spot. With both teams at 7-9 and 8-8 respectively, the outcome will determine the division champion, though Tampa needs a win plus a Falcons loss to clinch. Recent form and statistical edges set the stage for a tense matchup at Raymond James Stadium.

As previewed in the series overview, the NFL's 2025 Christmas Day Week 17 tripleheader carries playoff stakes and injury challenges. SportsLine models and DFS expert Mike McClure spotlight overs, underdog value, and high-upside players like Jahmyr Gibbs amid quarterback absences.

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The Tampa Bay Buccaneers host the Carolina Panthers on Saturday in a pivotal Week 18 matchup that will determine the NFC South champion. Tampa Bay, once early-season contenders, has struggled lately amid injuries and offensive inconsistencies. A victory is essential for the Buccaneers to extend their division dominance.

In the pivotal Week 16 of the 2025 NFL season—with clinching opportunities for multiple teams detailed in our prior coverage—CBS Sports and SportsLine experts deliver predictions and best bets. Odds via DraftKings Sportsbook feature spreads like Bills (-10) vs. Browns and Ravens (-3) vs. Patriots on Sunday Night Football.

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The Tampa Bay Buccaneers host the Atlanta Falcons on Thursday Night Football in Week 15, a matchup with significant playoff implications for the NFC South leaders. Both teams have struggled recently, with Tampa Bay holding a 7-6 record tied atop the division and Atlanta at 4-9 after seven losses in their last eight games. Key returns from injury could boost the Buccaneers' offense against a Falcons defense strong in sacks and pass defense.

The NFL regular season concludes on January 4, 2025, with Week 18 matchups that will finalize playoff seeds and division titles across both conferences. Key games include the Patriots seeking the AFC's top seed against the Dolphins, the Jaguars aiming to clinch the AFC South over the Titans, and the Eagles pursuing the NFC's No. 2 seed versus the Commanders. Analysts predict competitive finishes, with several underdogs poised to cover spreads amid resting starters and injury concerns.

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San Francisco 49ers quarterback Brock Purdy is preparing for a challenging matchup against the Seattle Seahawks' defense in Saturday's NFC Divisional Round game. After a tough 13-3 loss to Seattle in Week 18, where he threw for just 127 yards and an interception, Purdy emphasized the need to earn every yard. The 49ers aim to reverse their fortunes on the road, where Purdy holds a 4-0 record against the Seahawks.

 

 

 

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