Diseases and Conditions
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Blood-dwelling bacterium yields indole metabolites with anti-aging effects in skin cells
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Researchers have identified indole metabolites from the human blood bacterium Paracoccus sanguinis that showed anti-aging activity in laboratory-grown human skin cells. The compounds reduced oxidative stress, inflammation and collagen-degrading activity in cell experiments, according to findings published in the Journal of Natural Products.
Researchers have uncovered a neural signal involving the TRPV4 molecule that tells the brain when scratching an itch has provided enough relief. Experiments in mice showed that without this signal, scratching episodes become prolonged even as overall frequency drops.