Gut Microbiome
Global study highlights ‘hidden’ gut bacteria CAG-170 as a potential marker of health
Raportoinut AI AI:n luoma kuva Faktatarkistettu
Researchers led by the University of Cambridge report that an uncultured group of gut bacteria known as CAG-170 appears more abundant in healthy people and is less common in several chronic diseases, based on analysis of more than 11,000 gut metagenomes from 39 countries.
A retired US Marine officer in Massachusetts, plagued by a gut that brewed its own alcohol, has seen his symptoms resolve after receiving faecal transplants from a healthy donor. The treatment targeted the rare auto-brewery syndrome, where gut microbes ferment sugars into intoxicating levels of alcohol. This case highlights potential new avenues for managing the condition triggered by antibiotic use.
Raportoinut AI Faktatarkistettu
An international team of researchers has identified trimethylamine (TMA), a gut microbe metabolite produced from dietary nutrients such as choline, as a compound that inhibits the immune-signalling protein IRAK4, dampening inflammation and improving insulin action in experimental models. The discovery, reported in Nature Metabolism, suggests a potential new way to counter some of the harmful metabolic effects of high-fat diets and opens avenues for future type 2 diabetes therapies, a disease affecting more than 500 million people worldwide.