The Seattle Seahawks will face the San Francisco 49ers in the NFC Divisional Round on Saturday at Lumen Field, marking their third meeting this season. Seattle enters as a seven-point favorite after clinching the No. 1 seed with a 13-3 regular-season finale win over San Francisco. The winner advances to the NFC Championship Game amid high stakes and playoff trends favoring the road team in prior clashes.
The rivalry between the Seattle Seahawks and San Francisco 49ers intensifies with this NFC Divisional Round contest at Lumen Field in Seattle. It's the third time the NFC West foes meet in 2025, following San Francisco's narrow 17-13 victory in the season opener at the same venue and Seattle's decisive 13-3 triumph in Week 18 in Santa Clara, California, which secured the division title and the top playoff seed for the Seahawks.
Defensive tackle Jarran Reed expressed the team's disdain for their rivals, stating, "Me personally, don't like nothing about them." He emphasized the intensity ahead: "We know what's at stake; they know what's at stake. It's about getting out there between them lines and hitting it head-on, man-on-man, mano-y-mano."
Seattle finished the regular season 14-3 overall, tying for the NFL's best against-the-spread record at 12-5, and won their final seven games as favorites. However, the Seahawks have struggled in recent playoffs, going 0-3 straight-up and against the spread in their last three postseason games. San Francisco, at 13-5, overcame numerous injuries to exceed their preseason win total of 10.5 and boasts a 7-1 straight-up record in their last eight games, including four straight wins at Lumen Field against Seattle, covering the spread each time.
Betting odds list Seattle as a seven-point favorite at DraftKings, with the total dropping from an opening of 47.5 to around 44.5, reflecting unders in the teams' last three meetings. The road team has won and covered in both prior 2025 games. One prop bet highlights Brock Purdy under 230.5 passing yards, given Seattle's top-ranked pass defense and the 49ers' missing tight end George Kittle due to injury.
Expert Micah Roberts predicts the over on the total, citing San Francisco's potent offense against Seattle's defense: "They're going to give up a few scores and score a few more on their own. Over." This matchup promises a physical battle with playoff implications.
