The San Francisco 49ers, with a 9-4 record, will host the struggling Tennessee Titans, who stand at 2-11, on Sunday at Levi's Stadium. San Francisco aims to close the gap on NFC West leaders Los Angeles Rams and Seattle Seahawks, while Tennessee eyes the top draft pick. Kickoff is scheduled for 4:25 p.m. ET on FOX.
The 49ers enter Week 15 on a strong note, holding an 8-5 record against the spread and 7-6 to the over in their games this season. They have covered in four of their last five outings. Tennessee, meanwhile, has a 6-7 ATS mark and is 8-5 to the over, also covering four of its past five games. The Titans' overall record reflects their challenges, positioning them for a potential first overall selection in the 2024 NFL Draft.
Betting lines list the 49ers as 12.5-point favorites, with an over/under of 44.5 points. Money line odds are -901 for San Francisco and +604 for Tennessee. Viewers can catch the game on FOX or stream it via Fubo and the CBS Sports App.
A SportsLine Projection Model, which runs 10,000 simulations per game, favors the 49ers to win in 83% of outcomes and cover the spread in 53%. The model projects the over to hit in 67% of simulations. Its score prediction: 49ers 33, Titans 19.
Same-game parlay suggestions include the over 44.5, Christian McCaffrey over 5.5 receptions, and George Kittle scoring a touchdown anytime. San Francisco's push for playoffs adds stakes to this home contest.