Cortisol

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A large U.S. study has found that 27 percent of patients with resistant hypertension have hypercortisolism, an excess of the stress hormone cortisol. The MOMENTUM study, involving 1,086 participants across 50 centers, showed this condition is far more common than previously thought in those whose blood pressure remains high despite multiple medications. The discovery suggests screening for elevated cortisol could help explain treatment failures.

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