Sleep Aids

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Illustration of melatonin pills spilled on a nightstand with a symbolic cracked heart and monitor, representing study linking long-term use to heart risks.
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Preliminary study links yearlong melatonin use to higher risk of heart failure, hospitalization and death

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A preliminary analysis presented at the American Heart Association’s Scientific Sessions 2025 found that adults with chronic insomnia who used melatonin for a year or longer had higher rates of new heart failure, heart‑failure hospitalization and all‑cause death over five years than matched nonusers. The observational findings do not prove causation and are not yet peer‑reviewed.

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