Lakers host Spurs in Wednesday NBA matchup

The Los Angeles Lakers will host the San Antonio Spurs on Wednesday at 10 p.m. ET in a key Western Conference game. The Lakers enter with a 6-2 record despite LeBron James being sidelined with a back injury until at least mid-November, while the Spurs boast a 5-1 start led by Victor Wembanyama.

Wednesday's NBA schedule features 11 games, with the Lakers-Spurs tilt highlighted as a top matchup between two teams off to strong starts. The Lakers are favored by 2.5 points at home, with the over/under set at 227.5 points according to DraftKings odds. San Antonio's Victor Wembanyama is among the early frontrunners for NBA MVP honors.

LeBron James' absence due to a back injury will keep him out until mid-November, impacting the Lakers' lineup as they aim to maintain their momentum. The Spurs, riding a hot streak, look to continue their impressive early-season form against a Lakers team adjusting without their star forward.

This game is part of a busy night that also includes the undefeated Oklahoma City Thunder visiting the Portland Trail Blazers at 10 p.m. ET, where the Thunder are 4.5-point road favorites with an over/under of 230.5 points. Betting promotions like DraftKings' offer of $300 in bonus bets for a winning $5 wager and three months of free NBA League Pass are available for fans following the action.

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