The 2026 NFL season will feature seven brother-versus-brother clashes among the league's 17 active sibling pairs. These matchups include several first-time and rematch encounters across the regular season schedule.
Caleb Downs of the Dallas Cowboys is set to face his brother Josh Downs of the Indianapolis Colts. Josh noted that Caleb told him he would play nickel and said the matchup would be head-to-head all game. He added that it remains all fun and games but he plans to remind his younger sibling of their family order.
