Antimicrobial Resistance

Scientists uncover hidden antibiotic intermediate 100-fold more active than methylenomycin A

2025년 10월 29일 Heather Vogel 사실 확인됨

Researchers from the University of Warwick and Monash University report that pre-methylenomycin C lactone—an overlooked biosynthetic intermediate from Streptomyces coelicolor—shows more than a 100-fold increase in activity over methylenomycin A against Gram‑positive pathogens, including those behind MRSA and VRE. The finding adds momentum to efforts to tackle antimicrobial resistance, which was directly linked to an estimated 1.27 million deaths in 2019.