Ophthalmology

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Researchers at the Institute of Molecular and Clinical Ophthalmology Basel report that a high-throughput screen of more than 2,700 compounds in lab-grown human retinal organoids identified molecules that improved survival of cone photoreceptors—cells essential for sharp, color vision. The team linked the protective effect to inhibiting casein kinase 1 and says the results were also supported in a mouse model of retinal degeneration.

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A tiny wireless chip implanted in the eye, combined with smart glasses, has enabled many patients with advanced age-related macular degeneration to regain reading ability. In a clinical trial led by Stanford Medicine, 27 out of 32 participants achieved functional vision within a year. The findings, published in the New England Journal of Medicine, mark the first prosthetic device to provide form vision.

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