Psychiatry
RECOVER trial suggests vagus nerve stimulation benefits some patients with severe treatment-resistant depression for at least two years
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An implanted device that stimulates the vagus nerve was associated with sustained improvements in symptoms, functioning and quality of life among adults with long-standing, treatment-resistant major depression, according to researchers reporting two-year follow-up data from the ongoing RECOVER study led by Washington University School of Medicine in St. Louis.
Uppsala county's psychiatric ambulance, operating only eight hours a day, misses 60 to 80 percent of mental health alarms due to resource shortages. Hospital board chair Neil Ormerod (V) wants to extend operating hours but lacks funding. Police report a clear difference when the service is active.
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A woman in her 20s from Dalarna has been sentenced to forensic psychiatric care for multiple crimes against several relatives. The sentence covers instances of gross damage, home invasion, and threats. The offenses targeted close family members.
Scientists from Sweden, Denmark, and Germany have created a genetic test using polygenic risk scores to help predict which antidepressants and anti-anxiety medications will work best for individuals. The approach, tested on research databases, could reduce the trial-and-error process that affects nearly half of patients with depression or anxiety. Lead researcher Professor Fredrik Åhs envisions a future with cheap, effective tests to speed up relief for millions.
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Researchers from UC San Diego and 23andMe have discovered genetic links to cannabis use behaviors, connecting them to over 100 health traits. The study, published on October 13, 2025, in Molecular Psychiatry, highlights two key genes and could inform prevention of cannabis use disorder. It analyzed data from nearly 132,000 participants to explore early-stage risks.