Addiction

Fuatilia
Daniel Curtis Lee hands motel key to homeless co-star Tylor Chase outside Riverside motel as rainstorm approaches.
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Daniel Curtis Lee books motel for homeless 'Ned's Declassified' costar Tylor Chase

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In the latest support for former 'Ned's Declassified School Survival Guide' actor Tylor Chase amid his homelessness in Riverside, California, costar Daniel Curtis Lee drove from Los Angeles to book him a motel room ahead of a rainstorm. Devon Werkheiser expressed heartbreak and hope for recovery, while Shaun Weiss's earlier treatment offer was noted.

Jodie Sweetin opened up about her high school years on the Inside of You podcast. She described taking drugs and behaving worse than peers to counter assumptions she was stuck up after Full House ended.

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Young Hongkongers are increasingly accessing illegal online gambling via social media and chat groups, contributing to rising addiction problems.

New details in the investigation of director Rob Reiner and wife Michele Singer Reiner's fatal stabbing in Brentwood reveal no forced entry, a prior family dispute, and suspect son Nick Reiner's long battle with addiction, which inspired a father-son film.

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Researchers at Georgetown University Medical Center report that shifts in the brain protein KCC2 can change how strongly everyday cues become linked to rewards. In a study published December 9 in Nature Communications, they show that reduced KCC2 activity in rats is associated with intensified dopamine neuron firing and stronger cue–reward learning, offering clues to mechanisms that may also be involved in addiction and other psychiatric disorders.

Researchers at the University of Colorado Anschutz report that alcohol activates a metabolic pathway that generates fructose, which in turn fuels drinking behavior and liver injury in mice. The enzyme ketohexokinase (KHK) drives this process; inhibiting KHK reduced alcohol consumption and protected against liver damage in animal models.

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Researchers at McGill University have discovered that combining cannabis and tobacco use alters brain chemistry, potentially increasing anxiety and complicating quitting efforts. PET scans of young adults showed elevated levels of an enzyme that breaks down the mood-regulating 'bliss molecule' anandamide in co-users. The findings highlight a molecular mechanism behind worse outcomes for those using both substances.

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