Ketamine
PET brain scans link ketamine’s rapid antidepressant effect to shifts in AMPA receptor availability
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A study in Molecular Psychiatry used PET imaging with a new tracer to track changes in AMPA-type glutamate receptors in people with treatment-resistant depression receiving ketamine, reporting that region-specific receptor changes were associated with symptom improvement.
Jasveen Sangha, known as the 'Ketamine Queen,' received a 15-year prison sentence for her role in supplying ketamine that contributed to Matthew Perry's death. The drug dealer pleaded guilty last year to federal charges including distribution of ketamine resulting in death. Perry, the Friends star, died in October 2023 from the acute effects of the drug.
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The second doctor involved in Matthew Perry's tragic overdose has received a relatively lenient punishment. Dr. Mark Chavez was sentenced to eight months of home confinement and community service for his role in distributing ketamine to the actor. This comes after his colleague Dr. Salvador Plasencia got a harsher prison term earlier this month.