The No. 12 Purdue Boilermakers face the Indiana Hoosiers in a key Big Ten matchup on Tuesday, January 27, 2026. Purdue enters as a 5.5-point favorite after recent losses, while Indiana looks to build on a recent win. The game tips off at 9 p.m. ET in Bloomington, Indiana.
The upcoming clash between in-state rivals Purdue and Indiana highlights Tuesday's college basketball schedule. Purdue, with a 17-3 overall record and 7-2 in the Big Ten, has stumbled in its last two games, including an 88-82 defeat to Illinois on Saturday. Meanwhile, Indiana stands at 13-7 overall and 4-5 in conference play, snapping a four-game losing streak with an 82-59 victory over Rutgers on Friday.
The game will take place at Simon Skjodt Assembly Hall in Bloomington, Indiana. According to DraftKings Sportsbook, Purdue is listed as a 5.5-point favorite, with the over/under total set at 150.5 points, adjusted down from the opening line. The money line odds are Purdue at -221 and Indiana at +181.
SportsLine's Projection Model, which simulates games 10,000 times, has entered the week on a strong run, including 10-1 on top-rated over/under picks since last season and 6-0 on side picks. For this matchup, the model predicts the over on the total, noting Purdue's games have gone over in six of the last eight. Purdue ranks second in KenPom's offensive efficiency and eighth nationally in field-goal percentage.
Indiana's offense ranks 28th in efficiency, ahead of its 57th-ranked defense. The model forecasts Indiana's Lamar Wilkerson as the leading scorer with over 20 points, alongside eight players reaching double figures, for a combined total of 158 points. It projects the over hitting 65.3% of the time and one side of the spread succeeding nearly 60% of the time.
This rivalry game carries significance for both teams in the Big Ten standings, with Purdue aiming to rebound and Indiana seeking momentum.
