The Seattle Seahawks and San Francisco 49ers meet on Saturday night with the NFC West division title and the conference's No. 1 seed on the line. Both teams enter the matchup at Levi's Stadium with identical six-game winning streaks, Seattle at 13-3 and San Francisco at 12-4. The winner earns a first-round playoff bye, while the loser risks dropping in the seeding.
In one of the most pivotal games of the 2025 NFL regular season, the Seattle Seahawks visit the San Francisco 49ers on Saturday, January 3, at 8 p.m. ET in Santa Clara, California. The contest will decide the NFC West champion and the top overall seed in the NFC, granting the victor home-field advantage throughout the playoffs and a first-round bye.
Seattle, led by quarterback Sam Darnold, has completed 67.2% of his passes for 3,850 yards, 25 touchdowns, and 14 interceptions this season. Wide receiver Jaxon Smith-Njigba has been a key target, recording 113 receptions for 1,709 yards and 10 touchdowns in 16 games. The Seahawks' elite defense has fueled their surge, including a 28-10 victory over the Carolina Panthers last week. However, starting offensive lineman Charles Cross is out with a hamstring injury.
The 49ers counter with quarterback Brock Purdy, who has thrown for 2,040 yards, 20 touchdowns, and nine interceptions in eight games since returning from injury, completing 69.3% of his passes. Running back Christian McCaffrey anchors the offense, rushing for 1,179 yards and 10 touchdowns while catching 96 passes for 890 yards and seven scores. San Francisco's offense has averaged 455 yards and 42.3 points over their last three games. Tight end George Kittle is questionable with an ankle injury, joining receiver Ricky Pearsall and tackle Trent Williams on the injury report.
Odds list Seattle as a 2.5-point favorite with an over/under of 47.5 points. A SportsLine model projects 51 combined points and leans toward one side of the spread in over 50% of simulations. The teams split implications earlier, with San Francisco winning 17-13 in Week 1. This rematch could hinge on Darnold's ball security, as he leads the NFL with 14 interceptions and six lost fumbles.
