Bile Acids

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Bile acids hinder liver cancer immunotherapy, supplement may help

Heather Vogel

Scientists at the Salk Institute have found that certain bile acids in the liver suppress immune cells, reducing the effectiveness of immunotherapy for liver cancer. Supplementing with ursodeoxycholic acid (UDCA) reversed this effect in mice, shrinking tumors. UDCA, already approved for other liver conditions, could soon enter clinical trials for cancer treatment.

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