Biomedical Engineering
Texas A&M researchers build customizable living vessel-on-a-chip to mimic branching, aneurysms and stenosis
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Researchers at Texas A&M University say they have developed a customizable “vessel-chip” that recreates the complex shapes of human blood vessels—including branches, aneurysm-like bulges and stenosis-like narrowings—so scientists can study how altered blood flow affects endothelial cells and evaluate potential treatments without relying on animal models.
Biomedical engineers at Texas A&M University have used nanoflowers to make stem cells produce roughly twice the usual number of mitochondria. These enhanced stem cells then transfer the extra energy-producing organelles to damaged or aging cells, restoring their energy production and resilience in lab studies, according to a new report in the Proceedings of the National Academy of Sciences.
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Researchers at the University of Massachusetts Amherst have developed a nanoparticle-based cancer vaccine that prevented melanoma, pancreatic, and triple-negative breast cancers in mice. Up to 88% of vaccinated mice remained tumor-free, with the vaccine also stopping metastasis. The approach uses a 'super adjuvant' to trigger strong immune responses.