Most Brazilian states report severe acute respiratory syndrome (SRAG) at alert, risk, or high-risk levels, according to Fiocruz's InfoGripe bulletin released on April 29. Cases are driven mainly by influenza A and respiratory syncytial virus (RSV), which circulate more in autumn and winter. Exceptions are Rio de Janeiro, São Paulo, and Rio Grande do Sul.

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Brazil's Health Ministry confirmed the country's first case of Flu K, the H3N2 influenza A variant driving global alerts, in Pará state. This detection follows rising seasonal H3N2 circulation locally and comes amid the variant's dominance in the northern hemisphere.

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