Irritable Bowel Syndrome

Researchers at Cedars-Sinai analyzed nearly 20 years of health records from over 650,000 U.S. adults with irritable bowel syndrome, finding associations between certain medications and increased mortality. Antidepressants were linked to a 35% higher risk of death, while loperamide and diphenoxylate showed about double the risk compared to non-users. Other IBS treatments like FDA-approved drugs and antispasmodics showed no such increase.