mRNA
A large retrospective study from the University of Florida and The University of Texas MD Anderson Cancer Center, published in Nature, reports that patients with advanced non-small cell lung cancer or metastatic melanoma lived significantly longer if they received a Pfizer-BioNTech or Moderna COVID-19 mRNA shot within 100 days of starting immune checkpoint inhibitors. The authors stress the findings are observational and will require confirmation in randomized trials.
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An analysis of nearly 1,000 cancer patients shows that mRNA covid-19 vaccines, given soon after starting immune checkpoint inhibitors, nearly doubled survival times for advanced lung and skin cancers. The findings, presented at a medical congress in Berlin, suggest an unexpected immune boost from the vaccines. A clinical trial to confirm these results is set to begin before year's end.