UNAIDS welcomes South Africa’s Lenacapavir HIV prevention launch

UNAIDS has welcomed South Africa’s rollout of Lenacapavir as a landmark step in HIV prevention. The injectable is now available at 360 public health facilities across six provinces. The drug has also been added to the national essential medicines list.

South Africa launched the Lenacapavir HIV prevention programme on 6 June 2026. UNAIDS described the development as a landmark achievement for the country. The injectable is currently available at 360 public health facilities in six provinces. Officials have added the drug to South Africa’s essential medicines list. UNAIDS highlighted the rollout as an important measure to expand access to effective HIV prevention options.

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South Africa has started rolling out the twice-yearly HIV prevention injection lenacapavir, though success depends on managing interactions with common tuberculosis medicines.

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A new NGO report warns that lingering effects of 2025 US Pepfar funding cuts are undermining South Africa's rollout of the six-monthly HIV prevention injection lenacapavir, despite recent US funding restoration efforts and initial shipments. Community infrastructure losses hinder uptake among high-risk groups, even as rollout begins late May.

The World Health Organization has declared the Ebola outbreak in the Democratic Republic of the Congo and Uganda a public health emergency of international concern. South African health officials say the risk of spread to the country remains low but stress the need for continued vigilance.

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