The ABC drama delivered a shocking blow in its season 4 finale when Dr. Seth McDale died from internal injuries following a car crash. The tragedy unfolded just after his wife Angie Polaski gave birth to their daughter Edie.
Showrunners Liz Heldens, Karine Rosenthal and Daniel Thomsen confirmed they planned Seth's death from the start of the season to reunite Will and Angie. The character, played by Scott Foley, was killed off after treating Angie at the hospital, leaving her in deep grief while Will took a year-long leave to help raise the newborn.