Progeria

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A scientist in a lab examines cellular images representing lysosome activation in progeria research.
Billede genereret af AI

Lysosome activation clears progerin and eases cellular aging in progeria, study finds

Rapporteret af AI Billede genereret af AI Faktatjekket

Scientists in China report that repairing defects in lysosomes—the cell’s waste‑disposal hubs—accelerated clearance of progerin in patient cells and reduced markers of cellular aging, pointing to a potential therapeutic target for Hutchinson‑Gilford progeria syndrome.

Researchers report that a variant of the BPIFB4 gene enriched in long‑lived people improved markers of heart health in mouse and cell models of Hutchinson–Gilford progeria syndrome, suggesting a potential new path for therapy.

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