Lung Cancer
Study of young lung cancer patients finds unexpectedly high diet-quality scores; researchers probe possible pesticide exposure
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Preliminary research from USC Norris Comprehensive Cancer Center, presented at the American Association for Cancer Research (AACR) annual meeting, found that non-smokers diagnosed with lung cancer before age 50 reported eating more fruits, vegetables and whole grains—and had higher overall Healthy Eating Index scores—than the U.S. population average. The researchers emphasized that the results do not prove diet causes lung cancer and said a possible explanation could involve environmental exposures such as pesticides, a hypothesis that requires direct testing.
A study shows that advanced lung cancer patients receiving immunochemotherapy earlier in the day survive longer. A Hong Kong medical expert says the discovery opens possibilities for optimal treatment times, though more research is needed. The research was led by academics from Hunan Cancer Hospital in mainland China and supported by the Chinese University of Hong Kong’s faculty of medicine.
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Researchers in Japan have uncovered how cancer cells use tiny vesicles to spread the immune-suppressing protein PD-L1, explaining why immunotherapy often fails. A protein called UBL3 directs this process, but common statins can disrupt it, potentially boosting treatment effectiveness. The findings, from patient samples and lab tests, suggest a simple way to improve outcomes for lung cancer patients.
Scientists from the Francis Crick Institute and Vividion Therapeutics have developed chemical compounds that prevent the RAS gene from signaling tumor growth via the PI3K pathway. The treatment stopped tumor growth in mice models of lung and breast cancer without causing side effects like hyperglycemia. It is now entering human clinical trials.
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Researchers have identified a novel protein biomarker that detects lung cancer at an early stage with high accuracy. The discovery, detailed in a recent study, could enhance screening methods and improve patient outcomes. Clinical trials showed promising results in identifying the disease before symptoms appear.