The Tennessee Titans will host the New Orleans Saints in NFL Week 17 on Sunday, December 28, at 1 p.m. ET from Nissan Stadium. Playoff hopes are dim for both, shifting focus to young quarterbacks Tyler Shough (Saints) and Cam Ward (Titans). The Saints are 2.5-point road favorites with a total of 39.5 points.
Both teams notched Week 16 wins—Saints over the Jets, Titans over the Chiefs—but have little at stake in the 2025 NFL season's next-to-last week. The Titans (3-12) remain in contention for the No. 1 draft pick, while the Saints ride a three-game winning streak and hold a 7-8 against-the-spread record.
Quarterback play takes center stage: Shough has been solid lately for New Orleans, and Tennessee hopes last year's top draft pick Cam Ward builds momentum. The game airs on CBS and streams on Paramount+.
DraftKings odds list the Saints as 2.5-point favorites and Titans as +124 underdogs, with an over/under of 39.5. The Saints are 4-11 to the over, Tennessee 9-6, pointing to a potentially low-scoring game. The Titans are 7-7-1 ATS, showing resilience.
A SportsLine model simulating 10,000 times projects the Titans covering +2.5 in 51% of scenarios, winning outright in 46%, and the under hitting in 56%. Predicted score: Saints 22, Titans 21.
Suggested same-game parlay: Titans +2.5, under 39.5, Saints WR Chris Olave anytime touchdown.