Diet and Weight Loss

Brain recordings hint tirzepatide may briefly quiet ‘food noise’ before cravings return

December 08, 2025 Iniulat ng AI Larawang ginawa ng AI Fact checked

In a rare deep-brain recording study of a woman with severe obesity and loss-of-control eating, tirzepatide — sold as Mounjaro and Zepbound — temporarily silenced activity in a key reward region linked to “food noise,” or intrusive thoughts about food. About five months later, those brain signals and intense food preoccupation reappeared, suggesting the drug’s effects on this patient’s cravings were short‑lived.