Anemia
Study in rats finds long-term omeprazole use disrupts mineral levels linked to anemia and bone health risks
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Researchers in Brazil report that prolonged use of the proton pump inhibitor (PPI) omeprazole altered iron and calcium measures in adult rats and shifted how several minerals were distributed across organs—changes they say are consistent with higher risks of anemia and possible bone health harms. The authors and Brazil’s health regulator stress that PPIs remain effective for acid-related disorders, but warn against extended, unsupervised use.
Researchers have developed a three-in-one iron supplement combining iron, probiotics, and prebiotics to treat iron-deficiency anemia while preserving gut health. In studies on mice, the formula restored hemoglobin levels and balanced gut bacteria without causing inflammation. This innovation could improve anemia treatment by reducing common side effects of traditional supplements.