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Sugarcane-derived protein used in artificial saliva shows promise for protecting tooth enamel in lab tests
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Researchers in Brazil report that an artificial-saliva formulation made with a lab-modified sugarcane protein, CaneCPI-5 (also written CANECPI-5), can bind to tooth enamel and help reduce bacterial activity and mineral loss in laboratory experiments designed to model the severe dental risks faced by head and neck cancer patients after radiotherapy. The work, published in the Journal of Dentistry, found the formulation performed best when combined with fluoride and xylitol.
A 59,000-year-old tooth from a Siberian cave reveals that Neanderthals drilled into cavities to treat decay. The discovery pushes back the origins of dentistry by tens of thousands of years. Researchers identified clear marks from stone tools on the molar.
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Dr. Justin Scott, a dentist in Atlanta, has filed a petition to regain his license suspended by the Georgia Board of Dentistry over allegations of poor orthodontic work. His lawyer argues the board's action was unlawful after months of inaction following inspections. Patients have reported severe issues, including bone necrosis and loss of teeth.
Scientists at the University of Nottingham have developed a fluoride‑free, protein‑based gel that regenerates enamel‑like layers on teeth in ex vivo tests by mimicking natural growth processes. The study was published on November 4, 2025, in Nature Communications.
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Researchers have developed a gel that uses saliva-like properties to repair and regenerate tooth enamel, potentially preventing painful cavities. The innovation could offer a new alternative to traditional dental fillings. Clinical trials are planned for early next year.