HIV
Study links monocyte “biological aging” in blood to emotional depression symptoms in women with and without HIV
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A study of 440 participants from the Women’s Interagency HIV Study found that accelerated epigenetic aging in monocytes—an immune cell type—tracked more closely with emotional and cognitive depression symptoms such as hopelessness and loss of pleasure than with physical symptoms like fatigue. The work, published in The Journals of Gerontology: Series A, adds evidence that cell-type-specific aging measures could contribute to future biological tools to complement symptom-based depression screening, though researchers say more validation is needed before clinical use.
UNAIDS has welcomed South Africa’s rollout of Lenacapavir as a landmark step in HIV prevention. The injectable is now available at 360 public health facilities across six provinces. The drug has also been added to the national essential medicines list.
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A new combination pill containing bictegravir and lenacapavir shows promise for people with HIV who require complex regimens. The phase three ARTISTRY 1 study found it performed as well as existing multi-pill options. Experts note its impact in South Africa will likely remain limited.
Following a probe panel's preliminary findings, Madhya Pradesh has suspended the blood bank in-charge and two lab technicians at Satna's Sardar Vallabhbhai Patel Government Hospital, where six thalassemia children contracted HIV from infected blood transfusions. A show-cause notice was issued to the former civil surgeon.
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Nature Medicine has selected promising clinical studies for 2026, emphasizing long-lasting vaccines and innovative treatments. Key areas include tuberculosis, HIV, long Covid, stem cells, and cholesterol. These developments could transform the fight against global diseases.
The withdrawal of US aid since February 2025 has led to a significant drop in HIV viral load tests in South Africa, according to data from the National Health Laboratory Service. Public health experts warn this signals serious setbacks in the country's HIV management program. While viral rebound rates have decreased, the reasons remain unclear.
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An NPR report on September 12, 2025, highlighted the ongoing retreat of HIV worldwide, with fewer deaths, decreasing infections, and increased access to life-saving medications. These positive trends have persisted for decades.
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