Parkinson's Disease
Rachel Reid delays Unrivaled book to June 2027 for health reasons
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Author Rachel Reid has postponed the release of her novel Unrivaled from September 2026 to June 1, 2027, citing worsening Parkinson's symptoms and demands from recent fame. The book is the seventh in her Game Changers series and the third focused on hockey rivals Shane Hollander and Ilya Rozanov. Reid announced the delay in an Instagram video, emphasizing her commitment to quality.
Carlos Alberto Solari, known as 'the Indio' and former leader of the influential Argentine rock band Patricio Rey y sus Redonditos de Ricota, died on June 5 at age 77.
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Researchers at the Perelman School of Medicine at the University of Pennsylvania report that a protein called glycoprotein nonmetastatic melanoma B (GPNMB) may help drive the cell-to-cell spread of Parkinson’s-related alpha-synuclein pathology in lab models. In cultured-neuron experiments, antibodies designed to block GPNMB reduced the propagation of the toxic process, according to a study the team says was published in Neuron.
Duke-NUS Medical School researchers, working with the University of Sydney, have developed BrainSTEM—a two-tier, single-cell atlas of the developing human brain that profiles nearly 680,000 cells. Published online in Science Advances on October 31, 2025, the resource focuses on midbrain dopaminergic neurons, flags off‑target cell types in lab-grown models, and will be released openly for the research community.
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Scientists in the U.K. and Canada report the first direct visualization and measurement of alpha‑synuclein oligomers—the small protein clusters long suspected of triggering Parkinson’s—in human brain tissue. Using an ultra‑sensitive imaging method, the team found these clusters were larger and more numerous in Parkinson’s than in age‑matched controls, a result published in Nature Biomedical Engineering that may help guide earlier diagnosis and targeted therapies.