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Illustration of Mayo Clinic study revealing 90% gap in genetic screening for familial hypercholesterolemia, featuring lab scientists, DNA data, heart plaque model, and screening call-to-action.
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Mayo Clinic study finds major gaps in genetic screening for inherited high cholesterol

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A large Mayo Clinic study reports that current guidelines fail to detect nearly 90% of people with familial hypercholesterolemia, a common inherited cause of dangerously high cholesterol and early heart disease. Researchers analyzed exome data from more than 84,000 participants and found that most would not have been selected for standard genetic testing. Expanding routine DNA screening, they say, could help identify at-risk individuals earlier and prevent severe cardiovascular outcomes.

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