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Mayo Clinic study finds major gaps in genetic screening for inherited high cholesterol

8 december 2025 Rapporterad av AI Bild genererad av AI Faktagranskad

A large Mayo Clinic study reports that current guidelines fail to detect nearly 90% of people with familial hypercholesterolemia, a common inherited cause of dangerously high cholesterol and early heart disease. Researchers analyzed exome data from more than 84,000 participants and found that most would not have been selected for standard genetic testing. Expanding routine DNA screening, they say, could help identify at-risk individuals earlier and prevent severe cardiovascular outcomes.