Amelia Shepherd
The February 26, 2026, episode of Grey's Anatomy featured a tribute to late actor Eric Dane at its conclusion. Dane, who portrayed Dr. Mark Sloan, died on February 17 at age 53 after battling ALS. The episode also advanced storylines involving Amelia Shepherd's return and new romantic developments.
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In the January 29 episode of Grey's Anatomy season 22, Addison Montgomery returns to Grey Sloan Memorial, bringing urgent medical news and a personal bombshell about her marriage to Amelia Shepherd. The episode explores tensions in Addison's relationship with husband Jake while addressing patient crises and hospital staff developments.