Gastrointestinal Disease

Engineered bacterial ‘pills’ show promise for detecting gut bleeding in mice

22 ноября 2025 Сообщено ИИ Изображение, созданное ИИ Проверено фактами

Researchers have developed tiny ingestible hydrogel microspheres packed with engineered bacteria that glow when they encounter blood in the gut, potentially offering a quick, noninvasive way to monitor intestinal disease. In mouse models of colitis, the sensors detected heme — a component of blood — within minutes and produced stronger signals as disease severity increased.