Gastrointestinal Disease
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Engineered bacterial ‘pills’ show promise for detecting gut bleeding in mice
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Researchers have developed tiny ingestible hydrogel microspheres packed with engineered bacteria that glow when they encounter blood in the gut, potentially offering a quick, noninvasive way to monitor intestinal disease. In mouse models of colitis, the sensors detected heme — a component of blood — within minutes and produced stronger signals as disease severity increased.