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Dramatic illustration of the Rams overpowering an injured Cardinals team in their NFL Week 14 matchup at State Farm Stadium.
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Rams heavy favorites against depleted Cardinals in Week 14

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The Los Angeles Rams (9-3) face the Arizona Cardinals (3-9) on Sunday in Week 14 at State Farm Stadium, with the Rams aiming to rebound from a loss to Carolina and extend their lead in the NFC West. Arizona, mired in a four-game skid, will be without key players including quarterback Kyler Murray for the season and several offensive starters due to injuries. Betting odds list the Rams as 9.5-point road favorites with an over/under of 49 points.

The Cleveland Cavaliers will host the Orlando Magic on Monday night in an Eastern Conference battle at Rocket Arena. Cleveland enters on a hot streak after defeating Orlando 119-105 on Saturday, while the Magic seek to snap a three-game losing skid. Injuries will impact both sides, with key players sidelined.

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As previewed in the series overview, the NFL's 2025 Christmas Day Week 17 tripleheader carries playoff stakes and injury challenges. SportsLine models and DFS expert Mike McClure spotlight overs, underdog value, and high-upside players like Jahmyr Gibbs amid quarterback absences.

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