ALS
Study links microbial glycogen in the gut to inflammation in C9orf72-associated ALS and frontotemporal dementia
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Researchers at Case Western Reserve University report that some gut bacteria can make unusually inflammatory forms of glycogen and that this microbial glycogen can trigger immune activity linked to brain inflammation in models of disease tied to the C9orf72 mutation. In patient stool samples, the team found these glycogen forms more often in ALS and C9orf72-related frontotemporal dementia than in healthy controls, and enzymatically breaking down glycogen in the gut improved outcomes in mice.
Kalix becomes the first municipality in Sweden to carry out an artistic pilot project against ALS in collaboration with the Börje Salming ALS Foundation.
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Chris Johnson, the former Tennessee Titans running back, announced Monday that he was diagnosed with ALS last year. The 40-year-old shared details of his condition during a Good Morning America interview.
Researchers are exploring CAR T-cell therapy to slow the advancement of amyotrophic lateral sclerosis (ALS) by targeting overactive immune cells in the brain. The approach aims to reduce neuron damage without curing the disease. Early studies suggest potential benefits for other neurodegenerative conditions as well.
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Sander Severino, the Philippines' first world chess champion in para-chess, passed away on February 7, 2026, at the age of 40. His coach confirmed the news, highlighting Severino's historic achievements in international competitions. Tributes poured in from the Philippine Paralympic Committee, praising his dedication and resilience despite living with amyotrophic lateral sclerosis.