Lung Cancer
Scientists map proteins that let carcinomas change identity
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Researchers at Cold Spring Harbor Laboratory have identified key proteins and protein complexes that help certain carcinomas shift their cellular identity and potentially evade treatment. Two new studies, focusing on pancreatic cancer and tuft cell lung cancer, highlight molecular structures that could become targets for more precise and selective therapies.
Researchers in Japan have uncovered how cancer cells use tiny vesicles to spread the immune-suppressing protein PD-L1, explaining why immunotherapy often fails. A protein called UBL3 directs this process, but common statins can disrupt it, potentially boosting treatment effectiveness. The findings, from patient samples and lab tests, suggest a simple way to improve outcomes for lung cancer patients.
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The 82-year-old Copacabana crooner is giving fans a glimpse into his recovery. Barry Manilow posted a selfie from his hospital bed on Instagram, assuring everyone he's 'better today' amid treatment for a cancerous spot in his lung. Support is pouring in from his team as he reschedules tour dates.