Immuno-oncology

Cryo-expansion microscopy captures 3D architecture of killer T cells at the immune synapse, including in human tumors

April 30, 2026 由 AI 报道 AI 生成的图像 事实核查

Researchers from the University of Geneva and Lausanne University Hospital report they have visualized, in three dimensions and under near-native conditions, how cytotoxic T cells organize their killing machinery at the immune synapse. The work, published in Cell Reports, applies cryo-expansion microscopy to human T cells and to tumor tissue samples, providing nanoscale views intended to support immunology and cancer research.