Stroke

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Elderly man at dental exam with overlaid brain scan illustrating gum disease's link to brain white matter changes.
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Study links gum disease to greater white matter changes in the brain

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Research published October 22, 2025, in Neurology® Open Access reports that older adults with gum disease had more white matter hyperintensities—a marker of tissue damage—than peers without gum disease, even after accounting for other risks.

Two existing medications cooled core body temperature in animals after stroke and reduced brain damage. A small human trial showed limited effect due to slow delivery. Researchers are now planning a follow-up study with faster infusions.

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Epia Neuro, a newly launched startup in San Francisco, is developing a brain-computer interface to help stroke patients regain hand movement. The system combines a brain implant with a motorized glove. Stroke remains a leading cause of long-term disability, affecting hand and arm function in about two-thirds of survivors.

Researchers in Hungary have found that DMT, a natural psychoactive compound, significantly mitigates brain damage from stroke in animal models and cell cultures. The molecule restores the blood-brain barrier and curbs inflammation, potentially complementing current treatments. These discoveries, published in Science Advances, highlight DMT's therapeutic promise amid limited stroke options.

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