Pediatrician assessing overweight children in clinic, highlighting study-recommended early treatment to prevent adult risks like diabetes and hypertension.
Pediatrician assessing overweight children in clinic, highlighting study-recommended early treatment to prevent adult risks like diabetes and hypertension.
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Study recommends treatment for all children with obesity

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A new Karolinska Institutet study finds that children with moderate obesity face higher risks of type 2 diabetes, high blood pressure, and lipid disorders in adulthood, even without apparent risk markers. Researchers urge treatment for all such children.

A Karolinska Institutet study, published in Jama Pediatrics, tracked 7,200 children from the Boris quality registry to age 30. Groups included obesity with risk markers like abnormal blood and liver values or high blood pressure, obesity without markers, and a population control. At age 30, 17 percent in the first group developed type 2 diabetes, versus 9 percent without markers and 0.5 percent in controls. Similar patterns appeared for high blood pressure and elevated lipids. Claude Marcus, professor at Karolinska Institutet, stated: “Our results suggest that all children with obesity need treatment, even if they appear completely healthy on examination.” Previous views held that children with normal values likely did not require treatment. In a Dagens Nyheter debate article, three pediatric researchers note that nearly one in ten children with moderate obesity without metabolic impact develop type 2 diabetes before age 30. They criticize uneven regional care and TLV's lack of drug subsidies, despite national guidelines. Early weight loss reduced risk by 80 percent for those who succeeded.

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Split-image illustration depicting BMI vs. DXA scan misclassification in an Italian study, with adults and researchers in a clinic.
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Italian study finds BMI misclassifies more than one-third of adults when compared with DXA body-fat scans

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An Italian research team comparing standard BMI categories with dual-energy X-ray absorptiometry (DXA) body-fat measurements found that more than one-third of adults were placed in the wrong weight category, and that BMI slightly overestimated the combined prevalence of overweight and obesity in the sample.

New research published in Nature Medicine reveals that people with prediabetes can normalize blood sugar levels without losing weight. About one in four participants in lifestyle programs achieved this remission, offering protection against diabetes similar to weight loss methods. The key factors involve fat distribution and certain hormones.

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A major Spanish clinical trial has shown that a modified Mediterranean diet, combined with calorie restriction, physical activity and professional support, reduced the risk of type 2 diabetes by 31 percent over six years. The findings come from the PREDIMED-Plus study involving nearly 5,000 adults with overweight or obesity.

A new study shows that a high-fat ketogenic diet can normalize blood sugar levels in mice with hyperglycemia and enhance their muscles' response to exercise. Led by researcher Sarah Lessard, the research indicates that combining the diet with physical activity leads to better oxygen use and endurance. The findings suggest potential benefits for metabolic health when diet and exercise are paired.

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On World Kidney Day, March 12, knowledge about kidney disease is spread globally. About one in ten Swedes has impaired kidney function without symptoms, posing major health risks if detected late. The Njurföreningen Gävle-Dala urges Region Dalarna to implement routine testing at primary care centers to catch the disease early.

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